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dc.date.accessioned 2016-12-13T15:40:37Z
dc.date.available 2016-12-13T15:40:37Z
dc.identifier.uri https://digital.cic.gba.gob.ar/handle/11746/4971
dc.title Vanadium(IV) complexes inhibit adhesion, migration and colony formation of UMR106 osteosarcoma cells en
dc.type Artículo es
dcterms.abstract Vanadium is a trace element widely distributed in the environment. In vertebrates it is mainly stored in bone tissue. The unique cellular environment in the bone and the variety of interactions that mediate cancer metastasis determine that certain types of cancer, such as breast and prostate cancer, preferentially metastize in the skeleton. Since this eVect usually signiWes serious morbidity and grave prognosis there is an increasing interest in the development of new treatments for this pathology. The present work shows that vanadium complexes can inhibit some parameters related to cancer metastasis such as cell adhesion, migration and clonogenicity. We have also investigated the role of protein kinase A in these processes. en
dcterms.extent 7 p. es
dcterms.issued 2008
dcterms.language Inglés es
dcterms.license Attribution 4.0 International (BY 4.0) es
dcterms.subject Vanadium Metallicum en
dcterms.subject Cancer en
dcterms.subject Metastasis en
dcterms.subject Osteosarcoma en
cic.version info:eu-repo/semantics/submittedVersion es
dcterms.creator.author Molinuevo, María S. es
dcterms.creator.author Cortizo, Ana María es
dcterms.creator.author Etcheverry, Susana B. es
cic.lugarDesarrollo Universidad Nacional de La Plata es
dcterms.subject.materia Ciencias Químicas es
dcterms.isPartOf.issue vol. 61 es
dcterms.isPartOf.series Cancer Chemotherapy and Pharmacology es
cic.isPeerReviewed true es
cic.isFulltext true es


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