Automatic glycemic regulation for the pediatric population based on switched control and time-varying IOB constraints: an in silico study

cic.isFulltexttruees
cic.isPeerReviewedtruees
cic.lugarDesarrolloInstituto de Investigaciones en Electrónica, Control y Procesamiento de Señales (LEICI)es
cic.lugarDesarrolloUniversidad Nacional de La Plataes
cic.versioninfo:eu-repo/semantics/acceptedVersiones
dc.date.accessioned2021-03-17T12:04:50Z
dc.date.available2021-03-17T12:04:50Z
dc.identifier.urihttps://digital.cic.gba.gob.ar/handle/11746/10826
dc.titleAutomatic glycemic regulation for the pediatric population based on switched control and time-varying IOB constraints: an in silico studyen
dc.typeArtículoes
dcterms.abstractArtificial pancreas (AP) systems have shown to improve glucose regulation in type 1 diabetes (T1D) patients. However, full closed-loop performance remains a challenge particularly in children and adolescents, since these age groups often present the worst glycemic control. In this work, an algorithm based on switched control and timevarying insulin-on-board (IOB) constraints is presented. The proposed control strategy is evaluated in silico using the FDA-approved UVA/Padova simulator and its performance contrasted with the previously introduced Automatic Regulation of Glucose (ARG) algorithm in the pediatric population.The effect of unannounced meals is also explored. Results indicate that the proposed strategy achieves lower hypo- and hyperglycemia than the ARG for both announced and unannounced meals.en
dcterms.creator.authorFushimi, Emiliaes
dcterms.creator.authorSerafini, María Ceciliaes
dcterms.creator.authorDe Battista, Hernánes
dcterms.creator.authorGarelli, Fabricioes
dcterms.identifier.otherdoi:10.1007/s11517-020-02213-wes
dcterms.identifier.urlRecurso completoes
dcterms.isPartOf.issuevol. 58es
dcterms.isPartOf.seriesMedical & Biological Engineering & Computinges
dcterms.issued2020-06-24
dcterms.languageIngléses
dcterms.licenseAttribution-NonCommercial-NoDerivatives 4.0 Internacionales
dcterms.subjectArtificial pancreasen
dcterms.subjectSwitched controlen
dcterms.subjectInsulin on boarden
dcterms.subjectConstrained controlen
dcterms.subject.materiaIngeniería Eléctrica y Electrónicaes
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