Comparison of the effectiveness of microsatellites and SNP panels for genetic identification, traceability and assessment of parentage in an inbred Angus herd

cic.lugarDesarrolloUniversidad Nacional de La Plata es
dc.titleComparison of the effectiveness of microsatellites and SNP panels for genetic identification, traceability and assessment of parentage in an inbred Angus herden
dcterms.abstractDuring the last decade, microsatellites (short tandem repeats or STRs) have been successfully used for animal genetic identification, traceability and paternity, although in recent year single nucleotide polymorphisms (SNPs) have been increasingly used for this purpose. An efficient SNP identification system requires a marker set with enough power to identify individuals and their parents. Genetic diagnostics generally include the analysis of related animals. In this work, the degree of information provided by SNPs for a consanguineous herd of cattle was compared with that provided by STRs. Thirty-six closely related Angus cattle were genotyped for 18 STRs and 116 SNPs. Cumulative SNPs exclusion power values (Q) for paternity and sample matching probability (MP) yielded values greater than 0.9998 and 4.32E-42, respectively. Generally 2-3 SNPs per STR were needed to obtain an equivalent Q value. The MP showed that 24 SNPs were equivalent to the ISAG (International Society for Animal Genetics) minimal recommended set of 12 STRs (MP ~ 10-11). These results provide valuable genetic data that support the consensus SNP panel for bovine genetic identification developed by the Parentage Recording Working Group of ICAR (International Committee for Animal Recording).es
dcterms.creator.authorFernández, María Elenaes
dcterms.creator.authorGoszczynski, Daniel Estanislaoes
dcterms.creator.authorLirón, Juan Pedroes
dcterms.creator.authorVillegas Castagnasso, Egle Eteles
dcterms.creator.authorCarino, Mónica Herminiaes
dcterms.creator.authorRipoli, María Verónicaes
dcterms.creator.authorRogberg Muñoz, Andréses
dcterms.creator.authorPosik, Diego Manueles
dcterms.creator.authorPeral García, Pilares
dcterms.creator.authorGiovambattista, Guillermoes
dcterms.extentp. 185-191es
dcterms.identifier.otherDOI 10.1590/S1415-47572013000200008es
dcterms.identifier.urlRecurso completoes
dcterms.isPartOf.issuevol. 36, nº 2es
dcterms.isPartOf.seriesGenetics and Molecular Biologyes
dcterms.licenseAttribution 4.0 International (BY 4.0)es
dcterms.publisherSociedade Brasileira de Genéticaes
dcterms.subjectPolimorfismo de Nucleótido Simplees
dcterms.subject.materiaCiencias Biológicases
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