Identification of an intermediate for 1,8- dihydroxynaphthalene melanin synthesis in a race-2 isolate of Fulvia fulva (syn. Cladosporium fulvum)

cic.institucionOrigenCentro de Investigaciones de Fitopatología (CIDEFI)es
cic.isFulltexttruees
cic.isPeerReviewedtruees
cic.lugarDesarrolloCentro de Investigaciones de Fitopatología (CIDEFI)es
cic.versioninfo:eu-repo/semantics/submittedVersiones
dc.date.accessioned2019-01-30T13:22:15Z
dc.date.available2019-01-30T13:22:15Z
dc.identifier.urihttps://digital.cic.gba.gob.ar/handle/11746/8757
dc.titleIdentification of an intermediate for 1,8- dihydroxynaphthalene melanin synthesis in a race-2 isolate of Fulvia fulva (syn. Cladosporium fulvum)en
dc.typeArtículoes
dcterms.abstractFulvia fulva (syn. Cladosporium fulvum, Mycosphaerellaceae) is a dematiaceous fungus that causes tomato leaf mould. It is characterized by its biotrophic lifestyle and the synthesis of the bianthraquinone secondary metabolite, cladofulvin. The aim of the study was to characterize the dark pigment photochemically synthesized by F. fulva and to elucidate its biochemical pathway. We isolated a black pigment from in vitro cultures of the fungus. We determined the pigment to be 1,8- dihydroxynaphthalene (DHN)-melanin based on its chemical and photochemical characteristics, as well as the presence of flaviolin, when fungal reductases were inhibited by tricyclazole. Furthermore, the pks1 gene involved in pigment synthesis has a KS domain already associated with DHN-melanin. Our findings support the relevance of studying melanization in F. fulva.en
dcterms.creator.authorMedina, Rocíoes
dcterms.creator.authorLucentini, César Gustavoes
dcterms.creator.authorFranco, Mario Emilio Ernestoes
dcterms.creator.authorPetroselli, Gabrielaes
dcterms.creator.authorRosso, Janina Alejandraes
dcterms.creator.authorErra-Balsells, Rosaes
dcterms.creator.authorBalatti, Pedro Albertoes
dcterms.creator.authorSaparrat, Marioes
dcterms.extent21 p.es
dcterms.identifier.urlRecurso Completoes
dcterms.isPartOf.issuevol. 4, no. 12es
dcterms.isPartOf.seriesHeliyones
dcterms.issued2018-12-12
dcterms.languageIngléses
dcterms.licenseAttribution-NonCommercial-NoDerivatives 4.0 International (BY-NC-ND 4.0)es
dcterms.subjectBiochemistryen
dcterms.subjectGeneticsen
dcterms.subjectMicrobiologyen
dcterms.subjectMolecular biologyen
dcterms.subject.materiaCiencias Químicases
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