This dissertation examines the institutionalization of design programs in Argentine public national universities between 1958 and 2015 from a historical, comparative, and federal perspective. Using a multiple case study approach, it analyzes eight universities through institutional documents, curricula, official resolutions, and interviews. The findings show that the creation of design programs was closely linked to political, economic, productive, territorial, and educational contexts across different historical periods. The study proposes a plural genealogy of Argentine design and demonstrates that the development of design education was shaped by regional dynamics, public policies, and national development strategies.